MSology Library – Treating MS symptoms

Treating MS symptoms

Ampyra (dalfampridine)

Dalfampridine sustained-release for symptomatic improvement of walking speed in patients with multiple sclerosis. Jeffery & Pharr. Core Evid 2010;5:107-112. A review of dalfampridine studies to improve walking in MS. Phase III studies are published but are not available for free download. www.ncbi.nlm.nih.gov/pmc/articles/PMC3065554/pdf/ce-5-107.pdf

Cannabis (marijuana)

The therapeutic potential of cannabis and cannabinoids. Grotenhermen and colleagues. Dtsch Arztebl Int 2012;109:495-501. A review of how marijuana and related compounds may improve MS symptoms. www.ncbi.nlm.nih.gov/pmc/articles/PMC3442177/pdf/Dtsch_Arztebl_Int-109-0495.pdf

– Smoked cannabis for spasticity in multiple sclerosis: a randomized, placebo-controlled trial.
Corey-Bloom and colleagues. CMAJ 2012;184:1143-1150. This is the only study to look at the effect of smoking marijuana on MS symptoms. www.ncbi.nlm.nih.gov/pmc/articles/PMC3394820/pdf/1841143.pdf

Sex and sexuality

– A review of sexual differences in MS, including prevalence, immune mechanisms and hormonal effects. Harbo and colleagues. Ther Adv Neurol Disord 2013;6:237-248. www.ncbi.nlm.nih.gov/pmc/articles/PMC3707353/pdf/10.1177_1756285613488434.pdf

– A survey of sexual dysfunction among women with MS. Lew-Starowicz & Rola. Sex Disabil 2013;31:141-153. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3659270/pdf/11195_2013_Article_9293.pdf

 

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